The future of healthcare is being shaped today, and nurses have an important role in leading that transformation. In this issue, we explore how artificial intelligence is supporting clinical practice, improving efficiency, and creating new opportunities to enhance patient outcomes across Houston Methodist. From strengthening clinical decision-making to advancing patient care, AI is becoming an important part of our work. As we embrace these advances, we have an opportunity to shape how technology supports nursing, helping us innovate, lead change, and focus more of our time on what matters most: our patients. We invite you to explore this issue and discover what’s possible with AI at Houston Methodist.